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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CANX
All Species:
42.12
Human Site:
S583
Identified Species:
61.78
UniProt:
P27824
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27824
NP_001019820.1
592
67568
S583
E
D
E
I
L
N
R
S
P
R
N
R
K
P
R
Chimpanzee
Pan troglodytes
XP_001151304
592
67554
S583
E
D
E
I
L
N
R
S
P
R
N
R
K
P
R
Rhesus Macaque
Macaca mulatta
XP_001101429
592
67582
S583
E
D
E
I
L
N
R
S
P
R
N
R
K
P
R
Dog
Lupus familis
XP_533285
610
69806
S601
S
G
D
G
P
V
K
S
V
R
K
R
R
V
R
Cat
Felis silvestris
Mouse
Mus musculus
P35564
591
67259
S582
E
D
E
I
L
N
R
S
P
R
N
R
K
P
R
Rat
Rattus norvegicus
P35565
591
67236
S582
E
D
E
I
L
N
R
S
P
R
N
R
K
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506871
598
67609
S589
E
D
E
I
L
N
R
S
P
R
N
R
K
P
R
Chicken
Gallus gallus
NP_001025791
599
68090
S590
E
E
E
T
V
N
R
S
P
R
N
R
K
P
R
Frog
Xenopus laevis
NP_001080326
611
69964
S602
E
D
E
I
I
N
R
S
P
R
N
R
K
L
R
Zebra Danio
Brachydanio rerio
NP_998613
600
67856
S591
E
D
D
I
L
R
R
S
P
R
N
R
K
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
D399
D
E
S
K
Q
D
K
D
Q
S
E
H
D
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34652
619
69189
S603
T
E
E
F
A
K
K
S
P
K
N
T
G
G
A
Sea Urchin
Strong. purpuratus
XP_791226
591
66512
T580
A
P
K
E
K
A
T
T
P
K
K
P
K
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
D413
A
E
D
G
K
D
S
D
D
E
K
H
D
E
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29402
530
60468
A520
E
K
K
E
E
T
A
A
P
R
K
R
Q
P
R
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
T493
A
A
V
V
L
L
T
T
S
V
L
C
C
V
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
59.1
N.A.
93
93.5
N.A.
85.7
82.8
78.2
70.8
N.A.
31.7
N.A.
40.5
53.7
Protein Similarity:
100
99.8
99.4
75.2
N.A.
96.6
97.4
N.A.
93.1
90.8
86.2
84.1
N.A.
44.7
N.A.
58.9
69.7
P-Site Identity:
100
100
100
26.6
N.A.
100
100
N.A.
100
80
86.6
80
N.A.
0
N.A.
26.6
20
P-Site Similarity:
100
100
100
46.6
N.A.
100
100
N.A.
100
93.3
93.3
86.6
N.A.
26.6
N.A.
46.6
40
Percent
Protein Identity:
N.A.
29.3
N.A.
40
25.6
N.A.
Protein Similarity:
N.A.
44.4
N.A.
53.5
41.2
N.A.
P-Site Identity:
N.A.
0
N.A.
40
6.6
N.A.
P-Site Similarity:
N.A.
20
N.A.
60
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
7
0
0
7
7
7
7
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% C
% Asp:
7
50
19
0
0
13
0
13
7
0
0
0
13
0
0
% D
% Glu:
63
25
57
13
7
0
0
0
0
7
7
0
0
13
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
13
0
0
0
0
0
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% H
% Ile:
0
0
0
50
7
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
13
7
13
7
19
0
0
13
25
0
63
0
0
% K
% Leu:
0
0
0
0
50
7
0
0
0
0
7
0
0
7
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
50
0
0
0
0
63
0
0
0
0
% N
% Pro:
0
7
0
0
7
0
0
0
75
0
0
7
0
50
0
% P
% Gln:
0
0
0
0
7
0
0
0
7
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
7
57
0
0
69
0
69
7
0
75
% R
% Ser:
7
0
7
0
0
0
7
69
7
7
0
0
0
7
0
% S
% Thr:
7
0
0
7
0
7
13
13
0
0
0
7
0
7
0
% T
% Val:
0
0
7
7
7
7
0
0
7
7
0
0
0
13
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _